Use of electron microscopes in cell biology has revealed intricate structures in minute details but, there is always a limitation whereby only a tiny portion of the cell is captured and this misses out the bigger picture. On the contrary if low-res images are captured to view a greater part of the biological structure intricate details are missed out.
Team of scientists over at Leiden University Medical Center in the Netherlands have come up with a technique called “virtual nanoscopy” that enabled them to create a complete (almost) “micrograph of a zebrafish embryo encompassing 281 gigapixels in total at a resolution of 16 million pixels per inch” notes Phsy.org.
“Using the JCB DataViewer, anyone can navigate the zebrafish image from the level of the whole, 1.5 millimeter-long embryo down to subcellular structures.” it adds further.
Using this virtual nanoscopy technique, scientists can now map regions of cells and even tissue as large as 1 mm2 at nanometer resolution without actually missing out on the intricate details.